Former first lady Barbara Bush, wife of the nation’s 41st president and mother of the 43rd president, died at home in Houston, Texas, April 17. She was 92.

For many years, she suffered from a thyroid disorder called Graves’ disease, and had been in failing health. She was recently hospitalized for treatment of chronic obstructive pulmonary disease and congestive heart failure. Days before her death she announced she wanted no more treatments, just “comfort care” at home.

Born Barbara Pierce in New York City June 8, 1925, she was 16 when she met her future husband. They wed four years later at First Presbyterian Church in Rye, New York, on Jan. 6, 1945. They then moved to Midland, Texas.

She and President George H.W. Bush were the longest married of any presidential couple in U.S. history.

She was first lady of the United States from 1989 to 1993. She had previously served as second lady of the United States from 1981 to 1989, when her husband was vice president under Ronald Reagan.

She is survived by her husband, now 93, and their five children, 14 grandchildren and seven great-grandchildren.